Cellaris™ 1010 – Cell Labelling Kit (NIR-II)
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Description
Cellaris™ (formerly known as Luminicell Tracker™) contains highly emissive fluorescent organic nanoparticles, built for rapid labelling of live cells with great biocompatibility. They can be readily taken up by various types of cells within 1 hour. Once taken up by cells, they show intense luminescence with high photo-stability and possess durable signal for many cell generations with negligible cell toxicity.
Our cell labelling kit offers 10X brighter in fluorescence signal and 3X longer tracking duration as compared to commercially available products.
The labelled cells can be monitored using a variety of fluorescence techniques such as confocal microscopy, multi-photon microscopy and flow cytometry.
Cellaris contains organic nanoparticle-based fluorescence probe with novel aggregation induced emission (AIE) properties. Unlike conventional molecular dyes where they suffer from aggregation-caused quenching effects, AIE molecules are loaded and encapsulated in the core of nanoparticle, resulting in the high fluorescence intensities with minimal signal quenching, and unique spectral properties.
These nanoparticles are highly biocompatible, can be used for live-cells tracking for longitudinal studies.
#reagent
Key Benefits
10X Fluorescence Brightness
3X Signal Longevity
> 95% Cell Viability after 48 hours of incubation
> 10 Cell Generations of In Vitro Tracking
> 21 Days of In Vivo Tracking
> 99% Labelling Rate
High Cellular Retention
Zero Cross-Talk
Applications
Designed for applications in translational research, immune-oncology development, stem cell and gene therapy, drug development, 3D cell culture, in-vivo live-cell imaging etc.
Upon labelling, the long-lasting nature allows a wide variety of cell tracking applications both in vitro and in small animal models.
Cell differentiation, cell mobility, cell-cell interaction, etc. can be well studied with, as these nanoparticles have excellent cell retention and are not known to disrupt normal cell functions.
Labelled cells can be monitored using a variety of fluorescence techniques such as confocal microscopy, flow cytometry and in vivo imaging system.
Specifications
Organic nanoparticle-based fluorescence probe with AIE molecules
Particle size of 30 ± 5 nm
Stock concentration of 200 nM in ultrapure water
Recommended working concentration of 2-10 nM for labelling
Optical Properties
Absorption Maximum (nm) = 725
Emission Maximum (nm) = 1010
Compatible Laser Lines (nm) = 355/405/633/755*/808
*Denotes best excitation wavelength for fluorescent signal
Storage and Stability
Store at 2-8°C upon receipt. Do not freeze product.
Thaw at room temperature and vortex before use.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Price shown are for products only.
Additional shipping fees may be applied.
Supporting Documents
https://luminicell.com/pages/resources
Additional information
| Pack Size | Standard (500 µL), up to 100 tests, Half (250 µL), up to 50 tests, Trial (100 µL), up to 20 tests |
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